Table 8.

The Bethesda System for Reporting Thyroid Cytopathology: Risk of Malignancy and Recommended Clinical Management

Diagnostic CategoryRisk of Malignancy (%)**Usual Management
Nondiagnostic or unsatisfactory5-10Repeat FNA with ultrasound guidance
Benign0-3Clinical follow-up
Atypia of undetermined significance or follicular lesion of undetermined significance6-18Repeat FNA, molecular testing, or lobectomy
Follicular neoplasm or suspicious for a follicular neoplasm10-40Molecular testing, Lobectomy
Suspicious for malignancy45-60Near total thyroidectomy or lobectomy
Malignant94-96Near total thyroidectomy or lobectomy
FNA-fine needle aspiration
*Adapted with permission from Cibas and Ali ( 62 )
**

When NIFTP is not considered cancer

From: Fine-Needle Aspiration of the Thyroid Gland

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