CID/ML#Target NameIC50/ (nM) [SID, AID]Anti-target Name(s)IC50 (μM) [SID, AID]Fold SelectiveSecondary Assay(s) Name: IC50 (μM) [SID, AID]
CID 72737723/ML398Dopamine D4130 nM [SID 172236217; AID 743362]Dopamine D1, D2S, D2L, D3 and D5 receptors>20 μM [SID 172236217] [AID 743374, AID 743375, AID 743376, AID 743377, AID 743378]>100-foldDopamine D1, D2S, D2L, D3 and D5 receptors, >20 μM

From: Discovery and characterization of ML398, a potent and selective chiral morpholine based antagonist of the dopamine 4 (D4) receptor

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].
Copyright Notice

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.