Table 2.

Serum concentration of total thyroid hormones and TSH in patients with primary hypothyroidism of increasing severity

TSH (mU/L)
Group*T4 ug/dlT3 ng/dlBasalAfter 200 ug TRH
Control7.1±0.9115±311.3±0.511±4.6
16-9119±405.3±2.339±15
24-6103±2013±1092±50
32-4101±3563±56196±120
4<243±28149±144343±326

Results are mean ± SD. *Patients were categorized according to the severity of thyroid disease based on serum total T4 concentrations. (Adapted from Bigos et al. (118) with permission)

From: Physiology of the Hypothalamic-Pituitary-Thyroid Axis

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