Table A, Intravenous antibiotics for which PK/PD measures could be used - Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia

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Drug Class	Drug Subclass	Drug^a
Aminoglycosides	NA	Gentamicin^a Tobramycin^a Amikacin^a
Beta-lactams	Penicillins	Penicillin G Oxacillin Nafcillin
	Beta-lactam/beta-lactamase inhibitors	Ampicillin/sulbactam Piperacillin/tazobactam^a Ticarcillin/clavulanic acid^a
	Cephalosporins	Cefazolin Ceftriaxone Cefotaxime Ceftazidime^a Cefepime^a Ceftaroline
	Monobactams	Aztreonam^a
	Carbapenems	Doripenem^a Ertapenem Imipenem^a Meropenem^a
Fluoroquinolones	NA	Levofloxacin Ciprofloxacin Moxifloxacin
Glycopeptides	NA	Vancomycin^a
Glycylcyclines	NA	Tigecycline
Oxazolidinone	NA	Linezolid^a
Polymyxin	NA	Colistin (also called colistimethate sodium)
Rifamycins	NA	Rifampin Rifampicin
Tetracyclines	NA	Doxycycline Minocycline

: NA = not applicable; PK/PD = pharmacokinetic/pharmacodynamic.
a: Drug names in bold represent intravenous antibiotics most commonly used to treat hospital-acquired pneumonia.

Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia [Internet].

Comparative Effectiveness Reviews, No. 136.

Lux LJ, Posey RE, Daniels LS, et al.

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