Table 3Type III R-M genes predicted from H. pylori genome sequences

Genetic locus
26695J99GeneMra (kDa)Remarks
JHP1296mod-171.6
JHP1297res-191.4
HP1522JHP1411mod-273.1/72.9bORF contains frameshift in both strains; expression may be regulated by slipped-strand repair
HP1521JHP1410res-2111.5/111.685% protein identity
HP0593mod-368.4
HPO592res-3114.8
HP1369/1370mod-4a/4b93.9cORFs 1369 and 1370 probably comprise a single M gene; expression may be regulated by slipped- strand repair
HP1371res-4113.7
a

Predicted molecular mass of putative proteins expressed in strains 26695 and J99. Mr values for respective strains are separated by a slash.

b

Due to translational frameshift mutations, expression of these proteins is unlikely. Predicted protein molecular mass values are based on the presumed slipped-strand repair of the frameshift mutation in each strain.

c

Nucleotide sequence suggests that ORF encoded by mod-4 prematurely terminates downstream of homopolymeric G tract (residues 1402 to 1411). Predicted protein molecular mass is based on the presumed slipped-strand repair of the frameshift mutation.

From: Chapter 24, Restriction and Modification Systems

Cover of Helicobacter pylori
Helicobacter pylori: Physiology and Genetics.
Mobley HLT, Mendz GL, Hazell SL, editors.
Washington (DC): ASM Press; 2001.
Copyright © 2001, ASM Press.

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