Table 2Type II R-M genes predicted from H. pylori genome sequences

Genetic locus
26695J99FunctionaRemarks
jhp45MM.Tsp45I homolog
jhp46RETsp45I isoschizomer
HP0050jhp43MAdenine specific
jhp44M
HP0051MCytosine specific
HP0053REEam1105I isoschizomer
HP0054MM.Eam1105I homolog
HP0091jhp84REMboI isoschizomer; 3 frameshifts in J99 ORF
HP0092jhp85MM.MboI homolog
HP0260jhp244MAdenine specific
HP0262jhp246/247REOverlapping ORFs in J99 homologous to 26695 ORF
HP0263jhp248MCytosine specific
HP0478jhp430M
HP0479jhp431RE
HP0481jhp433M
HP0483jhp435M
jhp629MM.SecI homolog
jhp630RESecI homolog
jhp755REHpy99I
jhp756MM.Hpy99I
HPO669jhp613MAdenine specific
HP0909jhp845RE
HP0910jhp846MAdenine specific
HP0369JHP1012M
JHP1049REHhal isoschizomer
HP1121JHP1050MM.HhaI homolog
HP1208jhp1131MM.NlaIII homolog
HP1209RENlaIII isoschizomer (iceA1); contains frameshift mutation
HP1352JHP1271MM.HinfI homolog
HP1351JHP1270REHinfI isoschizomer
JHP1284M
HP1354JHP1272MAdenine specific
HP1368MM.MboIIB homolog
HP1367MM.MboIIA homolog
HP1366JHP1442REMboII isoschizomer; J99 ORF contains N-terminal truncation
HP1382JHP1295RE
HP1471JHP1364REExpression may be regulated by slipped-strand repair
HP1472JHP1365M
JHP1409M
Nonclassical R-M systems
HP0452REHomologous to McrB; 5-methylcytosine-specific
HP1517RE and MHomologous to Eco57I
a

M, methyltransferase; RE, restriction endonuclease

From: Chapter 24, Restriction and Modification Systems

Cover of Helicobacter pylori
Helicobacter pylori: Physiology and Genetics.
Mobley HLT, Mendz GL, Hazell SL, editors.
Washington (DC): ASM Press; 2001.
Copyright © 2001, ASM Press.

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