TABLE 5-8Summary of Cardiovascular Studies in Animals

SpeciesNOAEL
(mg/kg/d)		LOAEL
(mg/kg/d)		EffectsReference
MonkeysNone0.09Cerebrovasular changes, hypertension, intimal thickeningShaw et al. 1979
Rat0.05 (males)
0.06 (females)		0.28 (males)
0.34 (females)		Polyarteritis nodosa, calcification of arterial wallMitsumori et al. 1983, 1984
Spontaneous hypertensive ratNone2 (26 d)Increased blood pressure in femalesTamashiro et al. 1986
RatNone0.4HypertensionWakita 1987
RatNone12 (2 d)18% decrease in heart rateArito and Takahashi 1991

From: 5, HEALTH EFFECTS OF METHYLMERCURY

Cover of Toxicological Effects of Methylmercury
Toxicological Effects of Methylmercury.
National Research Council (US) Committee on the Toxicological Effects of Methylmercury.
Washington (DC): National Academies Press (US); 2000.
Copyright 2000 by the National Academy of Sciences. All rights reserved.

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