| Species | NOAEL | LOAEL | Effect | Reference | |
|---|---|---|---|---|---|
| Rat | None | 3.9 ppm in diet of dams | Reduced NK cell activity in pups | Ilbäck et al. 1991 | |
| Rat | None | 5 ppb in water | Altered mitogen response | Ortega et al. 1997 | |
| Rat | None | 5 ppb in water of dams | Increased thymic weight in pups | Wild et al. 1997 | Mouse |
| None | 1 ppm in diet | Increased mortality when infected with encephalitis virus | Koller 1975 | Mouse | |
| None | 3.9 ppm in diet | (0.5 mg/kg/d) | Reduced NK cell activity; decreased thymus weight. | Ilbäck 1991 | |
| Mouse | None | 3.69 ppm in diet of dams | Reduced resistance to Coxsackie B3 | Ilbäck et al. 1996 | |
| Mouse | None | 0.5 ppm in diet of dams | Altered immune effects in pups | Thuvander et al. 1996 | |
| Mouse | None | 3 ppm in water | Altered B-cell and T-cell subtypes; decreased GSH concentrations in splenocytes | Thompson et al. 1998 | |
| Mouse | None | 0.3 mg/kg/d | Antinucleolar antibody production | Hultman and Hansson-Georgiadis 1999 |
From: 5, HEALTH EFFECTS OF METHYLMERCURY
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