TABLE 4-4Alternative Medicines, Herbs, and Supplements Used for Weight Loss

Name/CompoundDescription
BladderwrackFucus vesiculosus
ChitosanPolymer of glucosamine derived from chitin
ChromiumCr—an essential element
CLAConjugated linoleic acid
DHEADehydroepiandrosterone
Ephedrine fat-burning stackEphedrine with caffeine and aspirin, ma huang with guarana and willow bark
Garcinia cambogiaContains hydroxycitrate (HCA)
GermanderTeucrium chamaedrys
HMBβ-Hydroxy-β-methylbutryrate
Olestra (Lawson et al., 1997)Mixture of hexa-, hepta-, and octa-esters of sucrose formed from long-chain fatty acids isolated from edible oils
PlantagoPlantain leaf or psyllium seed
PyruvateA 3-carbon compound
SunflowerHelianthus annuus
St. John's WortHypericum perforatum
SafetyEfficacy for Weight/Fat Loss
No, increases risk of hyperthyroidismInsufficient data
Insufficient dataNo (Pittler et al., 1999; Wuolijoki et al., 1999)
Yes, when used in recommended dosesLikely ineffective (Hallmark et al., 1996; Lukaski et al., 1996; Trent and Thieding-Cencel, 1995)
Yes, preliminary reportYes, preliminary report (Blankson et al., 2000)
NoYes, but studies are limited
Adverse effects have been reported (Haller and Benowitz, 2000; HHS/FDA, 1997; Shekelle et al., 2003)Yes, appropriate dose and in combination with caffeine (Astrup et al., 1992a, 1992b; Boozer et al., 2001)
Insufficient dataInsufficient data, possibly ineffective at dose of 1,500 mg/d in obese adults (Heymsfield et al., 1998)
NoInsufficient data
Yes, short-termYes
YesInsufficient data
Unknown, may cause gastrointestinal distress and affect absorption of medicationsInsufficient data
Insufficient dataNo
YesInsufficient data
Insufficient dataInsufficient data

SOURCE: Allison et al. (2001).

From: 4, Weight-Loss and Maintenance Strategies

Cover of Weight Management
Weight Management: State of the Science and Opportunities for Military Programs.
Institute of Medicine (US) Subcommittee on Military Weight Management.
Washington (DC): National Academies Press (US); 2004.
Copyright 2003 by the National Academy of Sciences. All rights reserved.

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