TABLE 2-1, Amount of Cigarette Smoke Constituents in Tobacco Smoke and Smoking Environments. Partial List of the Cigarette Smoke Constituents Generated in Mainstream and Secondhand Smoke in Amounts Exceeding 10 μg per Cigarette or That Have Been Shown to Be Cardiotoxic - Secondhand Smoke Exposure and Cardiovascular Effects

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Compound	Average Amount (μg per cigarette except where noted)	Present in Secondhand Smoke (>10 μg per cigarette)	Mean Concentration in Smoking Environments
Carbon dioxide	30,000
Carbon monoxide	20,000	Yes	0.2–33 ppm^a
Nicotine	1,650	Yes	0.6–106 μg/m³^a
Acetaldehyde	700		370–462 μg/m³^a
Acetic acid	570
Hydrogen cyanide	450
Formic acid	340
Nitrogen oxides	300		3–350 ppb^a
Formaldehyde	300	Yes	5–1,100 μg/m³^a
Methyl chloride	300
Benzene^b	30	Yes	2–100 μg/m³^a
Acetone	250
Catechol	195
1,3-butadiene^c	150	Yes	0.2–19 μg/m³^a
Toluene	150
Methanol	135
Hydroquinone	120
Lactic acid	120
Succinic acid	120
Phenol	100
Ammonia	100
Glycolic acid	100
4-vinylcatechol	84
Acrolein^c	80	Yes	14–100 μg/m³^a
Methylethylketone	70
3-cresol	60
4-cresol	60
Propionaldehyde	45		25–110 μg/m³^a
Resorcinol	44
3-methylfluoranthene	40
4-methylcatechol	38
3-methylcatechol	38
4-vinylphenol	30
2-methylfluranthene	30
Pyridine	30		1.34–6.5 μg/m³^a
Carbon disulfide	30	Yes
4-ethylcatechol	28
3-picoline	24
4-picoline	24
2-cresol	22
3-vinylpyridine	22	Yes
Cholesterol	22
Benzoic acid	20
3-ethylphenol	18
4-ethylphenol	18
Crotonaldehyde	15	Yes
2-methoxyphenol	13
2-picoline	12
Butyraldehyde	12	Yes
4-vinylguaiacol	11
Cadmium^c	0.5	Yes	3–10 ng/m³^d^,^e
Lead^c	0.4	Yes
Benzo[a]pyrene	0.075	Yes	0.4–22 ng/m³^a
Chromium^c	0.07		1.2–8.9 ng/m³^a
Nickel^c	0.05		2.5–7.2 ng/m³^a
Particulate matter	50^f	Yes	27–2,000 μg/m³^a

a: Data are from Jenkins et al., 1999.
b: Benzene concentration present in sidestream smoke is 163–353 μg per cigarette.
c: Amount is for sidestream smoke.
d: Data are from Bolte et al., 2008.
e: Data are from Brauer and Mannetje, 1998.
f: The concentration of particulate matter is in μm/m³.

Secondhand Smoke Exposure and Cardiovascular Effects: Making Sense of the Evidence.

Institute of Medicine (US) Committee on Secondhand Smoke Exposure and Acute Coronary Events.

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