Table 3. [Treatment of Manifestations in Individuals with IBMPFD]. - GeneReviews®

Manifestation/Concern	Treatment	Considerations/Other
Myopathy	Weight control	To avoid obesity
PT & stretching exercises	To promote mobility & prevent contractures
OT & use of mechanical aids (e.g., canes, walkers, orthotics, wheelchairs)	As needed for ambulation & mobility
Surgical intervention as needed for orthopedic complications (e.g., foot deformity, scoliosis)
Use of respiratory aids if indicated
Social & emotional support & stimulation	To maximize sense of social involvement & productivity & ↓ social isolation
Assisted living arrangements as necessitated by muscle weakness &/or dementia
Paget disease of bone	Treatment w/potent bisphosphonates	Can ↓ alkaline phosphatase concentration & relieve pain & disability

From: Inclusion Body Myopathy with Paget Disease of Bone and/or Frontotemporal Dementia

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