Table 1Summary of Assays and AIDs

PubChemBioAssay NameAIDsProbe TypeAssay TypeAssay FormatAssay Detection & well formatResponsible Center
Summary Assay for the inhibition of Hepatic Lipid Droplet Formation.1658InhibitorSummaryN/AN/ASBCCG
High Throughput Imaging Assay for Hepatic Lipid Droplet Formation.1656InhibitorPrimaryHCSFluorescence (staining) & 384-wellSBCCG
Single concentration confirmation of HCS identification of small molecules that inhibit hepatic lipid droplet formation463183InhibitorConfirmatory (Cherry Pick)HCSFluorescence (staining) & 384-wellSBCCG
Dose response confirmation of HCS identification of small molecules that inhibit hepatic lipid droplet formation463191InhibitorConfirmatory (Dose Response)HCSFluorescence (staining) & 384-wellSBCCG
SAR Analysis for the identification of small molecules that inhibit hepatic lipid droplet formation using an image based screen.493092; 504440InhibitorConfirmatory (Dry Powder)HCSFluorescence (staining) & 384-wellSBCCG
SAR Analysis for the identification of small molecules that inhibit hepatic lipid droplet formation in human hepatocytes using an image based screen.504422InhibitorSecondary (Dry Powder)HCSFluorescence (staining) & 384-wellSBCCG
Counterscreen for Detection of Compound Cytotoxicity in Hepatocytes (AML12 cells)463219; 463200InhibitorSecondary (Dose Response)HCSFluorescence (staining) & 384-wellSBCCG
SAR analysis of compound cytotoxicity in hepatocytes (AML12 cells) – by ATPLite™504443InhibitorSecondary (Dry Powder)HCSFluorescence (staining) & 384-wellSBCCG

From: Potent inhibitors of lipid droplet formation

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].

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