Table 10.

Treatment of Manifestations in Individuals with FXPOI

Manifestation/ConcernTreatmentConsiderations/Other
Infertility Referral to gynecologist or reproductive endocrinologistDiscuss contraception & fertility treatment options incl spontaneous conception, donor oocyte, & donor embryo in vitro fertilization.
Ovarian insufficiency Hormone replacementDue to risk of low bone mineral density & osteoporosis
Depression/Anxiety Referral to psychologist

From: FMR1 Disorders

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