Table 6, Percent of activity remaining for various kinases when inhibited by ML231 - Probe Reports from the NIH Molecular Libraries Program

Warning: The NCBI web site requires JavaScript to function. more...

Entry	Kinase	Family	% Activity Remaining	Entry	Kinase	Family	% Activity Remaining
1	AKT1(Full Length)	AGC	100.0	26	p38-g	CMGC	100.0
2	AKT2	AGC	100.0	27	PAK1	STE	100.0
3	AKT3	AGC	100.0	28	PDGFRB	TK	100.0
4	AMPK-a1	CAMK	100.0	29	PDK1	AGC	100.0
5	AURKA	Other	82.1	30	PIM1	CAMK	95.1
6	AURKB	Other	100.0	31	PIM2	CAMK	100.0
7	BLK	TK	100.0	32	PKA	AGC	100.0
8	CAMK1	CAMK	100.0	33	PKC-e	AGC	100.0
9	CAMK1G	CAMK	100.0	34	PKC-g	AGC	100.0
10	CAMK2B	CAMK	96.4	35	PKC-h	AGC	100.0
11	CAMKK1	Other	100.0	36	PRKD2	CAMK	93.1
12	CHEK1	CAMK	100.0	37	PKG1	AGC	100.0
13	CLK1	CMGC	71.7	38	PLK4	Other	100.0
14	CLK2	CMGC	79.4	39	PTK2	TK	99.1
15	DDR2	TK	100.0	40	PTK2B	TK	100.0
16	FLT1	TK	100.0	41	RPS6KA1	AGC	86.5
17	FLT3	TK	100.0	42	RPS6KA4	AGC	100.0
18	FYN	TK	100.0	43	SIK1	CAMK	100.0
19	GSK3-a	CMGC	64.7	44	SIK2	CAMK	100.0
20	IGFR1	TK	100.0	45	SLK	STE	90.1
21	MARK1	CAMK	100.0	46	SNARK	CAMK	90.6
22	MET	TK	100.0	47	SYK	TK	100.0
23	MLK1	TKL	100.0	48	TNK2	TK	100.0
24	MLK3	TKL	100.0	49	VEGFR2	TK	97.7
25	MST2	STE	100.0	50	YSK1	STE	100.0

Probe Reports from the NIH Molecular Libraries Program [Internet].

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.