| Entry | SID | CID | * |
 | Potency of GFP Clone in Yeast Assay n = # replicates | Cytotoxicity in Wildtypeb | IC50
(μM) of Sch9 Phosphoryl-ationc | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R3 | n | CIT2 EC50 μM (% Res)a | AGP1 EC50 μM (% Res)a | MEP2 EC50 μM (% Res)a | LAP4 EC50 μM (% Res)a | RPL19A EC50 μM (% Res)a | ||||||
| 1 | 99300522 | 3392161 | S | NO2 | 6 | 3.8 (91.7%) | > 100 | > 100 | > 100 | > 100 | 3 | 2.3 |
| 2 | 104169534 | 49842886 | S | H | 1 | > 100 | > 100 | > 100 | > 100 | > 100 | 3 | NA |
| 3 | 113234490 | 50918545 | S | CN | 2 | > 100 | > 100 | > 100 | > 100 | > 100 | 3 | NA |
| 4 | 110923095 | 50904404 | S | CO(3,4-dimethyl-phenyl) | 4 | > 100 | > 100 | > 100 | > 100 | > 100 | 3 | NA |
S = Synthesized, P = Purchased;
Percent Response at 100 μM test compound;
Scale of cell growth (0 = no growth; 3 = good growth);
NA: No data Available
From: Profiling a Selective Probe for RTG Branch of Yeast TORC1 Signaling Pathway
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