Table 6.

Recommended Surveillance for Individuals with Angelman Syndrome

System/ConcernEvaluationFrequency
Neurologic
  • Monitor those w/seizures as clinically indicated.
  • Assess for new manifestations incl seizures, changes in tone, movement disorders.
At each visit
Development
  • Monitor developmental progress & educational needs.
  • Speech assessment
Psychiatric/
Behavioral 		Behavioral assessment for hypermotoric/self-injurious behavior, sleep disturbance
Musculoskeletal Physical medicine, OT/PT assessment of mobility, self-help skills
Gastrointestinal Monitor for gastroesophageal reflux & constipation.
Nutrition/
Feeding
  • Measurement of growth parameters
  • Eval of nutritional status
  • Eval of older children for obesity
Eyes Ophthalmology examIn 1st yr if strabismus
is present; general
eval by age 2 yrs;
follow up per
ophthalmologist
Scoliosis Clinical examAnnually

OT = occupational therapy; PT = physical therapy

From: Angelman Syndrome

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