uptake inhibitor - Books

Result Filters

Results: 1 to 20 of 767 books (1907 items)

<< First< Prev

Page of 39

Next >Last >>

Select item 34012941.

Endotext [Internet].

Feingold KR, Anawalt B, Blackman MR, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

Top results in this book Table of Contents

Select item 15027922.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.

Top results in this book Table of Contents

Select item 44036683.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2024 Jan-.

Top results in this book Table of Contents

Select item 14152804.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

Top results in this book Table of Contents

Select item 26591825.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

York (UK): Centre for Reviews and Dissemination (UK); 1995-.

Top results in this book Table of Contents

Select item 23580526.

Probe Reports from the NIH Molecular Libraries Program [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2010-.

Top results in this book Table of Contents

Select item 16686907.

Holland-Frei Cancer Medicine. 6th edition.

Kufe DW, Pollock RE, Weichselbaum RR, et al., editors.

Hamilton (ON): BC Decker; 2003.

Top results in this book Table of Contents

Select item 52412088.

The Heterogeneity of Cancer Metabolism [Internet]. 2nd edition.

Le A, editor.

Cham (CH): Springer; 2021.

Top results in this book Table of Contents

Select item 14589849.

GeneReviews® [Internet].

Adam MP, Feldman J, Mirzaa GM, et al., editors.

Seattle (WA): University of Washington, Seattle; 1993-2024.

Top results in this book Table of Contents

Select item 485381610.

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet].

Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-.

Top results in this book Table of Contents

Select item 139544811.

Electrochemical Methods for Neuroscience.

Michael AC, Borland LM, editors.

Boca Raton (FL): CRC Press/Taylor & Francis; 2007.

Top results in this book Table of Contents

Select item 188138212.

Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 6th edition.

Siegel GJ, Agranoff BW, Albers RW, et al., editors.

Philadelphia: Lippincott-Raven; 1999.

Top results in this book Table of Contents

Select item 282152413.

PDQ Cancer Information Summaries [Internet].

Bethesda (MD): National Cancer Institute (US); 2002-.

Top results in this book Table of Contents

Select item 238715614.

Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition.

Noebels JL, Avoli M, Rogawski MA, et al., editors.

Bethesda (MD): National Center for Biotechnology Information (US); 2012.

Top results in this book Table of Contents

Select item 144161815.

Helicobacter pylori: Physiology and Genetics.

Mobley HLT, Mendz GL, Hazell SL, editors.

Washington (DC): ASM Press; 2001.

Top results in this book Table of Contents

Select item 553046816.

Cardiovascular Signaling in Health and Disease [Internet].

Parinandi NL, Hund TJ, editors.

Cham (CH): Springer; 2022.

Top results in this book Table of Contents

Select item 536791017.

Prevention and Treatment of Atherosclerosis: Improving State-of-the-Art Management and Search for Novel Targets [Internet].

von Eckardstein A, Binder CJ, editors.

Cham (CH): Springer; 2022.

Top results in this book Table of Contents

Select item 489133018.

Addendum to NICE guideline CG61, Irritable bowel syndrome in adults: Diagnosis and management of irritable bowel syndrome in primary care.

London: National Institute for Health and Care Excellence (NICE); 2015 Feb. (NICE guideline, No. CG61.1.)

Top results in this book Table of Contents

Select item 420372019.

Streptococcus pyogenes : Basic Biology to Clinical Manifestations [Internet].

Ferretti JJ, Stevens DL, Fischetti VA, editors.

Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2016-.

Top results in this book Table of Contents

Select item 538153420.

Screening for Depression, Anxiety, and Suicide Risk in Children and Adolescents: An Evidence Review for the U.S. Preventive Services Task Force [Internet].

Viswanathan M, Wallace I, Middleton JC, et al.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2022 Oct. (Evidence Synthesis, No. 221.)

Top results in this book Table of Contents

<< First< Prev

Page of 39

Next >Last >>

Supplemental Content

Images search in Bookshelf

Figure 3

Regulation of initiation of coagulation by TFPI. The subcellular targeting of the inhibitor to glycosphingolipid-rich rafts allows for reversible regulation of TF on the cell surface. TFPI at higher concentrations can also bind to transmembrane proteoglycan receptors that facilitate LRP-mediated uptake and degradation by the clathrin-coated pits pathway.

Regulation of Tissue Factor Expression.

Madame Curie Bioscience Database [Internet]. Austin (TX): Landes Bioscience; 2000-2013.
Figure 3Comparison of ML312 to Prior Art Compounds with DiI-HDL Uptake

ML312 was tested against prior art compounds (ML278, ML279, R-154716, BLT-1 and ITX-5061) in the DiI-HDL uptake assay. Each compound was tested over a range of concentrations up to 35 μM. Concentration response curves were generated using GeneData Condeseo and show normalized percent activity for the individual doses (AID 624029), ML312, IC₅₀ = 0.12 μM (A); ML278 IC₅₀ = 0.005 μM (B); ML279, IC₅₀ = 0.012 μM (C); BLT-1, IC₅₀ = 0.005 μM (D); ITX-5061, IC₅₀ = 0.15 μM (E); and R-154716, IC₅₀ = 0.004 μM (F). Note: 1 μM BLT-1 data points appear as a tight column because this dose of BLT-1 was used as the positive control and tested in dose in separate wells. ○ =replicate 1, △=replicate 2.

A Small Molecule Inhibitor of Scavenger Receptor BI-mediated Lipid Uptake - Probe 3.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
Figure 2Dose Response Curves for the Probe (ML312)

ML312 was used over a range of concentrations up to 35 μM in the primary DiI-HDL uptake assay, IC₅₀=0.06 μM (AID 623880) (A), Alexa-488 HDL binding assay, AC₅₀ = 0.44 μM (AID 624024) (B), 24-h CellTiter-Glo cytotoxicity, IC₅₀ > 35 μM (AID 623895) (C), and the DiI-HDL ldlA7 counterscreen, IC₅₀ >35 μM (AID 624007) (D). Dose curves were generated with Genedata Condeseo and shows normalized percent activity for the individual doses. ○=replicate 1, △=replicate 2

A Small Molecule Inhibitor of Scavenger Receptor BI-mediated Lipid Uptake - Probe 3.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
Figure 4

57-year-old woman with history of 2 HL relapses, the last one treated by Nivolumab. One year after starting nivolumab (PD1 immune check point inhibitor), she developed enlarged mediastinal and abdominal lymph nodes, diffuse pulmonary lesions (SUVmax=27.4) and a hepatic lesion, all with intense FDG uptake A, Biopsies revealed aseptic granuloma including well-formed giant cells consistent with sarcoid-like reaction. PET/CT after corticosteroids (b) showed improvement with a complete metabolic response of all lesions.

Hodgkin Lymphoma: Recent Progress in Overall Management.

Gallamini A, Juweid M, editors. Lymphoma [Internet]. Brisbane (AU): Exon Publications; 2021 Dec 28.