3,5-Dinitroisonicotinic acid - Books

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Select item 26591821.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

York (UK): Centre for Reviews and Dissemination (UK); 1995-.

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Select item 14589842.

GeneReviews® [Internet].

Adam MP, Feldman J, Mirzaa GM, et al., editors.

Seattle (WA): University of Washington, Seattle; 1993-2024.

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Select item 23580523.

Probe Reports from the NIH Molecular Libraries Program [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2010-.

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Select item 15027924.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.

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Select item 54576705.

TOXICOLOGICAL PROFILE FOR ARSENIC.

Atlanta (GA): Agency for Toxic Substances and Disease Registry (US); 2007 Aug.

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Select item 43841886.

Occupational Exposures to Mists and Vapours from Strong Inorganic Acids; and Other Industrial Chemicals.

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.

Lyon (FR): International Agency for Research on Cancer; 1992. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 54.)

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Select item 34012947.

Endotext [Internet].

Feingold KR, Anawalt B, Blackman MR, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Select item 18602428.

WormBook: The Online Review of C. elegans Biology [Internet].

Pasadena (CA): WormBook; 2005-2018.

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Select item 52389969.

Report on Carcinogens Monograph on Haloacetic Acids Found as Water Disinfection By-Products: RoC Monograph 12 [Internet].

National Toxicology Program.

Research Triangle Park (NC): National Toxicology Program; 2018 Mar.

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Select item 243457210.

Fat Detection: Taste, Texture, and Post Ingestive Effects.

Montmayeur JP, le Coutre J, editors.

Boca Raton (FL): CRC Press/Taylor & Francis; 2010.

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Select item 563221611.

National Cancer Institute’s Nanotechnology Characterization Laboratory Assay Cascade Protocols [Internet].

Bethesda (MD): National Cancer Institute (US); 2005 May 1-.

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Select item 290697612.

TRP Channels.

Zhu MX, editor.

Boca Raton (FL): CRC Press/Taylor & Francis; 2011.

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Select item 290889213.

Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.

Benzie IFF, Wachtel-Galor S, editors.

Boca Raton (FL): CRC Press/Taylor & Francis; 2011.

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Select item 528121214.

A Randomized, Double-Blind, Placebo Controlled Study of the Efficacy of Lithium for the Treatment of Pediatric Mania Followed by an Open Label Long-Term Safety Period, Double-Blind, Placebo-Controlled Discontinuation Phase, and Open Label Restabilization Period (COLT2) [Internet].

Findling R, Taylor-Zapata P, Anand R, et al.; Eunice Kennedy Shriver National Institute of Child Health and Human Development.

Bethesda (MD): National Institute of Child Health and Human Development (US); 2015 Dec 1.

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Select item 308968615.

Neurobiology of Chemical Communication.

Mucignat-Caretta C, editor.

Boca Raton (FL): CRC Press/Taylor & Francis; 2014.

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Select item 165410616.

Immunobiology: The Immune System in Health and Disease. 5th edition.

Janeway CA Jr, Travers P, Walport M, et al.

New York: Garland Science; 2001.

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Select item 542588817.

Evidence review for the clinical and cost-effectiveness of intra-articular injections for the management of osteoarthritis: Osteoarthritis in over 16s: diagnosis and management: Evidence review J.

London: National Institute for Health and Care Excellence (NICE); 2022 Oct. (NICE Guideline, No. 226.)

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Select item 432404018.

Some Aromatic Amines, Organic Dyes, and Related Exposures.

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.

Lyon (FR): International Agency for Research on Cancer; 2010. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 99.)

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Select item 305467619.

Toxicological Profile for Chromium.

Wilbur S, Abadin H, Fay M, et al.

Atlanta (GA): Agency for Toxic Substances and Disease Registry (US); 2012 Sep.

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Select item 554587020.

Toxicological Profile for Chlorine.

Atlanta (GA): Agency for Toxic Substances and Disease Registry (US); 2010 Nov.

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Figure 2

Metabolism of 2-Ethylhexyl p-Methoxycinnamate in Rodents

Introduction.

National Toxicology Program. NTP Developmental and Reproductive Toxicity Technical Report on the Modified One-Generation Study of 2-Ethylhexyl p-Methoxycinnamate (CASRN 5466-77-3) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats with Prenatal, Reproductive Performance, and Subchronic Assessments in F1 Offspring: DART Report 06 [Internet]. Research Triangle Park (NC): National Toxicology Program; 2022 Jun.
Figure 44-1

Major pathways of branched-chain amino acid metabolism. Maple syrup urine disease is caused by a congenital deficiency of reaction 2. Many of the primary organic acidurias, for example, isovaleric acidemia and methylmalonic acidemia, are referable to inherited defects of enzymes involved in the oxidation of organic acids derived from the branched-chain amino acids. Enzymes: 1, branched-chain amino acid transaminase; 2, branched-chain amino acid decarboxylase; 3, isovaleryl-CoA dehydrogenase; 4, glycine-N-acylase; 5, 3-methylcrotonyl-CoA carboxylase; 6, crotonase; 7, 3-methylglutaconyl-CoA hydratase; 8, 3-OH-3-methylglutaryl-CoA lyase; 9, 2-ketothiolase; 10, isobutyryl-CoA dehydrogenase; 11, propionyl-CoA carboxylase; 12, methylmalonyl-CoA mutase; 13, 3-OH-isobutyryl-CoA deacylase. TPP, thiamine pyrophosphate; LipA, lipoic acid; ETF, electron transfer flavoprotein; AdoB₁₂, adenosylcobalamin; IVA, isovaleric acid; IVG, isovalerylglycine; TCA, tricarboxylic acid.

Diseases of Amino Acid Metabolism.

Siegel GJ, Agranoff BW, Albers RW, et al., editors. Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 6th edition. Philadelphia: Lippincott-Raven; 1999.
Figure 3-2Proposed Metabolic Pathways of Methoxychlor

(b) CYP = cytochrome P-450
(c) Estrogenic compound
(d) Metabolite identified in excreta
(e) Mono-OH-MXC = 2-(p-Methoxyphenyl)-2-(p-hydroxyphenyl)-1,1,1-trichloroethane
(f) Bis-OH-MXC = 2,2-Bis(p-hydroxyphenyl)-1,1,1-trichloroethanol (HPTE)
(g) MDDE = Methoxydiphenyldichloroethylene
Proposed Metabolic Pathways of Methoxychlor Key to Metabolite Chemical Names
1. Bis(4-methoxyphenyl)acetic acid Methoxy Diphenyl Acetic Acid
2. α-(4-hydroxyphenyl)-α-(4-methoxyphenyl)acetic acid Hydroxyphenyl Methoxyphenyl acetic acid
3. Bis(4-hydroxyphenyl)acetic acid Bis-OH-Diphenyl acetic acid CASRN: 40232-93-7
4. 4,4-Dihydroxybenzophenone Bis-OH-Benzophenone CASRN: 611-99-4
5. 1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane Methoxychlor (MXC) CASRN: 72-43-5
6. 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane Mono-OH-MXC 2-(p-Methoxyphenyl)-2-(p-hydroxyphenyl)-1,1,1-trichloroethane
7. 1,1,1-Trichloro-2,2-bis(4-hydroxyphenyl)ethane Bis-OH-MXC 2,2-Bis(p-hydroxyphenyl)-1,1,1-trichloroethanol (HPTE) CASRN: 2971-36-0
8. 1,1,1-Trichloro-2-(3,4-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethane Tris-OH-MXC
9. 1,1-Dichloro-2,2-bis(4-methoxyphenyl)ethene Methoxy-DDE (MDDE) Methoxydiphenyldichloroethylene CASRN: 2132-70-9
10. 1,1-Dichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethene Mono-OH-MDDE
11. 1,1-Dichloro-2,2-bis(4-hydroxyphenyl)ethene Bis-OH-MDDE CASRN: 14868-03-2

HEALTH EFFECTS.

Toxicological Profile for Methoxychlor. Atlanta (GA): Agency for Toxic Substances and Disease Registry (US); 2002 Sep.
Figure 14.

Distribution of the amino acid residues of the human GR susceptible to acetylation, phosphorylation, ubiquitination or SUMOylation. Human GR has 4 acetylation sites (lysines: K at amino acid position 480, 492, 494 and 495, shown with “A”), at least 5 phosphorylation sites (serines: S at amino acid position 45, 203, 211, 226 and 395, shown with “P”), 1 ubiqitination site (Lysine: K at amino acid position 419, shown with “U”) and 3 SUMOylation sites (Lysines: K at amino acid position 277, 293 and 703, shown with “S”).

Glucocorticoid Receptor.

Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.