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Effect of depletion of HIF-1α, FACT or RNF20/40 on gene expression in hypoxia of MCF7 breast cancer cells

(Submitter supplied) To investigate how HIF-1 recruits FACT and RNF20/40 to mediate histone ubiquitination and facilitate transcription of target genes, we established stable cell lines in which HIF-1, FACT or RNF20/40 has been knocked down by shRNA. We performed gene expression profiling analysis using data obtained from RNA-seq of 4 different cells at 20% and 1% oxygen condition.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
24 Samples
Download data: XLSX
Series
Accession:
GSE217204
ID:
200217204

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