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Organizing biological data
Proliferation and differentiation of intestinal stem cells depends on the zinc finger transcription factor BCL11/Chronophage
Whole exome sequencing for indentification of specific gene mutations in an Indian cohort of triple-negative breast cancer patients
This study analyzed whole exome sequencing data from 15 Indian triple-negative breast cancer (TNBC) patients. On average, 106 mutations per sample were identified. The most significant recurrent mutations were found in genes including CTNNB1, TP53, and SLC7A8. Other cancer-associated genes also showed mutations. The TNBC genomes exhibited predominant mutational signatures related to spontaneous deamination, DNA repair failure, and transcriptional strand bias. These mutations were involved in several major signaling pathways. The findings highlight key exonic mutations in Indian TNBC patients that could be used for screening, risk prediction, and developing targeted therapeutics. Further studies on genetic variability among TNBC patients are suggested for improved treatment strategies.
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Improved detection of methylation in ancient DNA
Metagenomic analysis of soil microbiota under fluoride stress in the Purulia District, West Bengal, India
Using conserved protein to mRNA ratios across kingdoms to enhance microbial functional predictions
Analysis of the bronchoalveolar lavage fluid microbial flora in COPD patients at different lung function during acute exacerbation
Paenibacillus sp. BC-1
Paenibacillus sp. BC-1 Genome sequencing
The Bladder Tumor Microbiome May Augment Response to Bacillus Calmette Guerin (BCG) in Non-Muscle Invasive Bladder Cancer
Association of immune evasion in myeloid sarcomas with disease manifestation and patients’ survival
Association of immune evasion in myeloid sarcomas with disease manifestation and patients' survival
RNAseq data of human myeloid sarcomas
Treponema_pallidum_strain_diversity_in_Africa_and_Asia___MAGUS
Paenibacillus tarimensis
Paenibacillus tarimensis Genome sequencing
Omnigene-Gut ensures fecal microbiome stability in the pediatric population
Omnigene-Gut in the pediatric population
Integrated electrophysiological and genomic profiles of single cells reveal spiking tumor cells in human glioma [scRNA-seq]
Integrated electrophysiological and genomic profiles of single cells reveal spiking tumor cells in human glioma [Patch-Seq]
Analysis of the rice jasmonate receptors OsCOIs
To decipher the molecular responses controlled in rice by the jasmonate receptors OsCOIs, mutated lines edited either in both the OsCOI1a and OsCOI1b genes or in the OsCOI2 gene were generated and analyzed.
Effect of Se on the liver metabolism in mice via RNA-seq
Effect of ZEA on the intestine of piglets
Effect of ZEA on the intestine of piglets Raw sequence reads
A type 2 diabetes DNA methylation signature in monocytes exhibits ethnic specificity preferentially for Native Hawaiians
Nanopore sequencing of Deschampsia antarctica for the whole genome assembly
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