8Y6I: P-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in nanodisc

PDB ID: 8Y6IDownload
MMDB ID: 245600
PDB Deposition Date: 2024/2/2
Updated in MMDB: 2024/04
Experimental Method:
electron microscopy
Resolution: 2.54  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 8Y6I: trimeric; determined by author and by software
Molecular Components in 8Y6I
Label Count Molecule
Proteins (3 molecules)
1
Atp-dependent Translocase Abcb1,mneongreen
Molecule annotation
1
Uic2 FAB Light Chain
Molecule annotation
1
Uic2 FAB Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
12
CHOLESTEROLCHOLESTEROL
2
1
1,2-Distearoyl-sn-glycerophosphoethanolamine1,2-Distearoyl-sn-glycerophosphoethanolamine
3
3
elacridarelacridar
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303