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8QIC:
Structure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors
PDB ID:
8QIC
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MMDB ID:
245212
PDB Deposition Date:
2023/9/13
Updated in MMDB:
2024/04
Experimental Method:
x-ray diffraction
Resolution:
2.5 Å
Source Organism:
Escherichia coli IAI1
Similar Structures:
VAST+
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Biological Unit for 8QIC: dimeric; determined by author and by software (PISA)
Molecular Components in 8QIC
Label
Count
Molecule
Proteins (2 molecules)
A
D
2
Threonine--trna Ligase
Chemicals and Non-standard biopolymers (8 molecules)
1
2
2-oxidanyl-5-[[4-(phenylmethyl)phenyl]sulfamoyl]benzoic acid
2
4
GLYCEROL
3
2
ZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303