8JD3: Cryo-EM structure of Gi1-bound mGlu2-mGlu3 heterodimer

PDB ID: 8JD3Download
MMDB ID: 232006
PDB Deposition Date: 2023/5/12
Updated in MMDB: 2023/10
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8JD3: pentameric; determined by author
Molecular Components in 8JD3
Label Count Molecule
Proteins (5 molecules)
1
Metabotropic Glutamate Receptor 2
(Gene symbol: GRM2)
Molecule annotation
1
Metabotropic Glutamate Receptor 3
(Gene symbol: GRM3)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
(Gene symbol: GNAI1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
1-butyl-3-chloranyl-4-(4-phenylpiperidin-1-yl)pyridin-2-one1-butyl-3-chloranyl-4-(4-phenylpiperidin-1-yl)pyridin-2-one
2
2
GLUTAMIC ACIDGLUTAMIC ACID
3
3
CHOLESTEROLCHOLESTEROL
4
1
DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINEDI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303