National Center for
Biotechnology Information

8IUL: Cryo-EM structure of the latanoprost-bound human PTGFR-Gq complex

PDB ID:

MMDB ID:

232890

PDB Deposition Date:

2023/3/24

Updated in MMDB:

2024/10

Experimental Method:

electron microscopy

Resolution:

2.78 Å

Source Organism:

Mus musculus▼

Taxonomy	Molecule
Mus musculus	E
Homo sapiens	A, B, G, R

Similar Structures:

Biological Unit for 8IUL: pentameric; determined by author

Molecular Components in 8IUL
Label	Count	Molecule
Proteins (5 molecules)
A	1	G Subunit Alpha (Q)
B	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
E	1	Antibody Fragment Scfv16
G	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
R	1	Prostaglandin F2-alpha Receptor
Chemical and Non-standard biopolymers (1 molecule)
1	1	Z-7-[(1R,2R,3R,5S)-3,5-bis(oxidanyl)-2-[(3R)-3-oxidanyl-5-phenyl-pentyl]cyclopentyl]hept-5-enoic acid

* Click molecule labels to explore molecular sequence information.

Citing MMDB