7YYZ: Molecular snapshots of drug release from tubulin: 10 microseconds after photoactivation

PDB ID: 7YYZDownload
MMDB ID: 226985
PDB Deposition Date: 2022
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 7YYZ: trimeric; determined by author and by software (PISA)
Molecular Components in 7YYZ
Label Count Molecule
Proteins (3 molecules)
1
Tubulin Alpha-1b Chain
Molecule annotation
1
Tubulin Beta-2b Chain
Molecule annotation
1
Designed Ankyrin Repeat Protein (Darpin) D1
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
CALCIUM IONCALCIUM ION
4
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
5
1
Azo-Combretastatin A4 (trans)Azo-Combretastatin A4 (trans)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303