7W48: Crystal structure of the gastric proton pump complexed with PF-03716556

PDB ID: 7W48Download
MMDB ID: 210466
PDB Deposition Date: 2021/11/26
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 7W48: dimeric; determined by author and by software (PISA)
Molecular Components in 7W48
Label Count Molecule
Proteins (2 molecules)
1
Potassium-transporting Atpase Alpha Chain 1
(Gene symbol: ATP4A)
Molecule annotation
1
Potassium-transporting Atpase Subunit Beta
(Gene symbol: ATP4B)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
2
O-DODECANYL OCTAETHYLENE GLYCOLO-DODECANYL OCTAETHYLENE GLYCOL
3
3
RUBIDIUM IONRUBIDIUM ION
4
1
N-(2-hydroxyethyl)-N,2-dimethyl-8-[[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino]imidazo[1,2-a]pyridine-6-carboxamideN-(2-hydroxyethyl)-N,2-dimethyl-8-[[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino]imidazo[1,2-a]pyridine-6-carboxamide
5
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
6
1
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303