7UFB: CYP3A4 bound to an inhibitor

PDB ID: 7UFBDownload
MMDB ID: 218439
PDB Deposition Date: 2022/3/22
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 7UFB: dimeric; determined by author
Molecular Components in 7UFB
Label Count Molecule
Proteins (2 molecules)
2
Cytochrome P450 3A4
(Gene symbol: CYP3A4)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
2
(2R)-3-phenyl-2-({(2S)-3-phenyl-2-[2-(pyridin-3-yl)acetamido]propyl}sulfanyl)-N-[(pyridin-3-yl)methyl]propanamide(2R)-3-phenyl-2-({(2S)-3-phenyl-2-[2-(pyridin-3-yl)acetamido]propyl}sulfanyl)-N-[(pyridin-3-yl)methyl]propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303