7R1U: Crystal structure of SARS-CoV-2 nsp10/nsp16 in complex with the WZ16 inhibitor

PDB ID: 7R1UDownload
MMDB ID: 216977
PDB Deposition Date: 2022/2/3
Updated in MMDB: 2022/09
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 7R1U: dimeric; determined by author
Molecular Components in 7R1U
Label Count Molecule
Proteins (2 molecules)
1
2'-o-methyltransferase Nsp16
Molecule annotation
1
Non-structural Protein 10
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
(2S,5S)-2,6-diamino-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}hexanoic acid(2S,5S)-2,6-diamino-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}hexanoic acid
2
1
P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATEP1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE
3
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
4
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303