7PFO: Core human replisome

PDB ID: 7PFODownload
MMDB ID: 237013
PDB Deposition Date: 2021/8/11
Updated in MMDB: 2023/10
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 7PFO: 21-meric; determined by author and by software (PISA)
Molecular Components in 7PFO
Label Count Molecule
Proteins (19 molecules)
1
DNA Replication Licensing Factor Mcm2
(Gene symbol: MCM2)
Molecule annotation
1
DNA Replication Licensing Factor Mcm3
(Gene symbol: MCM3)
Molecule annotation
1
DNA Replication Licensing Factor Mcm4
(Gene symbol: MCM4)
Molecule annotation
1
DNA Replication Licensing Factor Mcm5
(Gene symbol: MCM5)
Molecule annotation
1
DNA Replication Licensing Factor Mcm6
(Gene symbol: MCM6)
Molecule annotation
1
DNA Replication Licensing Factor Mcm7
(Gene symbol: MCM7)
Molecule annotation
1
DNA Polymerase Epsilon Subunit 2
(Gene symbol: POLE2)
Molecule annotation
1
DNA Polymerase Epsilon Catalytic Subunit a
(Gene symbol: POLE)
Molecule annotation
1
Cell Division Control Protein 45 Homolog
(Gene symbol: CDC45)
Molecule annotation
1
DNA Replication Complex Gins Protein Psf1
(Gene symbol: GINS1)
Molecule annotation
1
DNA Replication Complex Gins Protein Psf2
(Gene symbol: GINS2)
Molecule annotation
1
DNA Replication Complex Gins Protein Psf3
(Gene symbol: GINS3)
Molecule annotation
1
DNA Replication Complex Gins Protein Sld5
(Gene symbol: GINS4)
Molecule annotation
3
WD Repeat and Hmg-box DNA-binding Protein 1
(Gene symbol: WDHD1)
Molecule annotation
1
Protein Timeless Homolog
(Gene symbol: TIMELESS)
Molecule annotation
1
Timeless-interacting Protein
(Gene symbol: TIPIN)
Molecule annotation
1
Claspin
(Gene symbol: CLSPN)
Molecule annotation
Nucleotides(2 molecules)
1
Leading Strand DNA
Molecule annotation
1
Lagging Strand DNA
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
5
3
3
1
* Click molecule labels to explore molecular sequence information.

Citing MMDB