National Center for
Biotechnology Information

7ABG: Human pre-Bact-1 spliceosome

PDB ID:

7ABG Download

MMDB ID:

198419

PDB Deposition Date:

2020/9/7

Updated in MMDB:

2024/05

Experimental Method:

electron microscopy

Resolution:

7.8 Å

Source Organism:

synthetic construct▼

Taxonomy	Molecule
synthetic construct	Z
Homo sapiens	A5, A2, z, F, D, W, B, s, Q, A1, 5, L, R, V, 9, C, H, J, 2, A3, K, y , G, A, I, P, p, 4, A4, u, T, E, w, x, v, 0, N, r, Y, 6, A6, h, i, m, l, k, j, n, f, g, a, e, c, b, d, q, X

Similar Structures:

Biological Unit for 7ABG: 58-meric; determined by author

Molecular Components in 7ABG
Label	Count	Molecule
Proteins (54 molecules)
A5	1	Nuclear Cap-binding Protein Subunit 1
A2	1	U6 Snrna-associated Sm-like Protein Lsm7
z	1	Splicing Factor 3B Subunit 6
F	1	Splicing Factor 3A Subunit 2
D	1	U5 Small Nuclear Ribonucleoprotein 40 KDA Protein
W	1	U2 Small Nuclear Ribonucleoprotein A'
B	1	U2 Small Nuclear Ribonucleoprotein B''
s	1	U5 Small Nuclear Ribonucleoprotein 200 KDA Helicase
Q	1	Protein Bud31 Homolog
A1	1	Nuclear Cap-binding Protein Subunit 2
L	1	Cell Division Cycle 5-like Protein
R	1	Spliceosome-associated Protein Cwc15 Homolog
V	1	U6 Snrna-associated Sm-like Protein Lsm2
9	1	U6 Snrna-associated Sm-like Protein Lsm3
C	1	U6 Snrna-associated Sm-like Protein Lsm4
H	1	U6 Snrna-associated Sm-like Protein Lsm5
J	1	U6 Snrna-associated Sm-like Protein Lsm6
A3	1	U6 Snrna-associated Sm-like Protein Lsm8
K	1	Microfibrillar-associated Protein 1
y	1	PHD Finger-like Domain-containing Protein 5A
G	1	Pleiotropic Regulator 1
A	1	Pre-mrna-processing-splicing Factor 8
I	1	Pre-mrna-splicing Factor 38A
P	1	Pre-mrna-splicing Factor Rbm22
p	1	Splicing Factor 3A Subunit 1
4	1	Splicing Factor 3A Subunit 3
A4	1	Transcription Elongation Regulator 1
u	1	Splicing Factor 3B Subunit 1
T	1	Splicing Factor 3B Subunit 2
E	1	Splicing Factor 3B Subunit 3
w	1	Splicing Factor 3B Subunit 4
x	1	Splicing Factor 3B Subunit 5
v	1	SNW Domain-containing Protein 1
0	1	Smad Nuclear-interacting Protein 1
N	1	Zinc Finger Matrin-type Protein 2
r	1	116 KDA U5 Small Nuclear Ribonucleoprotein Component
Y	1	Serine/arginine Repetitive Matrix Protein 1
A6	1	Serine/arginine-rich Splicing Factor 1
h a	2	Small Nuclear Ribonucleoprotein SM D2
i b	2	Small Nuclear Ribonucleoprotein F
m f	2	Small Nuclear Ribonucleoprotein-associated Proteins B and B'
l e	2	Small Nuclear Ribonucleoprotein SM D3
k d	2	Small Nuclear Ribonucleoprotein G
j c	2	Small Nuclear Ribonucleoprotein E
n g	2	Small Nuclear Ribonucleoprotein SM D1
q	1	Ubiquitin-like Protein 5
X	1	WW Domain-binding Protein 11
Nucleotides(4 molecules)
5	1	U5 Snrna
2	1	U2 Snrna
Z	1	Minx M3 Pre-mrna
6	1	U6 Snrna
Chemicals and Non-standard biopolymers (4 molecules)
1	1	INOSITOL HEXAKISPHOSPHATE
2	1	GUANOSINE-5'-TRIPHOSPHATE
3	1	MAGNESIUM ION
4	1	7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE

* Click molecule labels to explore molecular sequence information.

Citing MMDB

Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303