6ZOG: Minocycline binding to the deep binding pocket of AcrB-I38F_I671T

PDB ID: 6ZOGDownload
MMDB ID: 202042
PDB Deposition Date: 2020/7/7
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 2.75  Å
Source Organism:
Escherichia coli K-12▼
Similar Structures:
Biological Unit for 6ZOG: pentameric; determined by author and by software (PISA)
Molecular Components in 6ZOG
Label Count Molecule
Proteins (5 molecules)
3
Multidrug Efflux Pump Subunit Acrb
Molecule annotation
2
Darpin
Molecule annotation
Chemicals and Non-standard biopolymers (31 molecules)
1
6
DODECYL-BETA-D-MALTOSIDEDODECYL-BETA-D-MALTOSIDE
2
2
DECANEDECANE
3
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
(2S)-3-hydroxypropane-1,2-diyl didecanoate(2S)-3-hydroxypropane-1,2-diyl didecanoate
5
1
PENTADECANEPENTADECANE
6
1
OctadecaneOctadecane
7
1
(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE
8
5
GLYCEROLGLYCEROL
9
1
N-OCTANEN-OCTANE
10
3
SULFATE IONSULFATE ION
11
1
DODECANEDODECANE
12
1
PHOSPHATIDYLETHANOLAMINEPHOSPHATIDYLETHANOLAMINE
13
1
TETRADECANETETRADECANE
14
1
DECYLAMINE-N,N-DIMETHYL-N-OXIDEDECYLAMINE-N,N-DIMETHYL-N-OXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303