6ZO6: Minocycline binding to the deep binding pocket of AcrB-G619P

PDB ID: 6ZO6Download
MMDB ID: 202032
PDB Deposition Date: 2020/7/7
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Escherichia coli K-12▼
Similar Structures:
Biological Unit for 6ZO6: pentameric; determined by author and by software (PISA)
Molecular Components in 6ZO6
Label Count Molecule
Proteins (5 molecules)
3
Multidrug Efflux Pump Subunit Acrb
Molecule annotation
2
Darpin
Molecule annotation
Chemicals and Non-standard biopolymers (83 molecules)
1
6
DODECYL-BETA-D-MALTOSIDEDODECYL-BETA-D-MALTOSIDE
2
3
N-OCTANEN-OCTANE
3
5
DECYLAMINE-N,N-DIMETHYL-N-OXIDEDECYLAMINE-N,N-DIMETHYL-N-OXIDE
4
14
GLYCEROLGLYCEROL
5
3
DODECANEDODECANE
6
6
HEXANEHEXANE
7
24
1,2-ETHANEDIOL1,2-ETHANEDIOL
8
2
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
9
1
(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE
10
1
(2S)-3-hydroxypropane-1,2-diyl didecanoate(2S)-3-hydroxypropane-1,2-diyl didecanoate
11
5
DECANEDECANE
12
3
CHLORIDE IONCHLORIDE ION
13
2
PENTADECANEPENTADECANE
14
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
15
1
OctadecaneOctadecane
16
1
HEXADECANEHEXADECANE
17
1
SULFATE IONSULFATE ION
18
1
TETRADECANETETRADECANE
19
1
PHOSPHATIDYLETHANOLAMINEPHOSPHATIDYLETHANOLAMINE
20
1
(2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate(2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate
21
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303