6XTX: CryoEM structure of human CMG bound to ATPgammaS and DNA

PDB ID: 6XTXDownload
MMDB ID: 188068
PDB Deposition Date: 2020/1/16
Updated in MMDB: 2020/07
Experimental Method:
electron microscopy
Resolution: 3.29  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6XTX: dodecameric; determined by author and by software (PISA)
Molecular Components in 6XTX
Label Count Molecule
Proteins (11 molecules)
1
DNA Replication Licensing Factor Mcm2
Molecule annotation
1
DNA Replication Licensing Factor Mcm3
Molecule annotation
1
DNA Replication Licensing Factor Mcm4
Molecule annotation
1
DNA Replication Licensing Factor Mcm5
Molecule annotation
1
DNA Replication Licensing Factor Mcm6
Molecule annotation
1
DNA Replication Licensing Factor Mcm7
Molecule annotation
1
DNA Replication Complex Gins Protein Psf1
Molecule annotation
1
DNA Replication Complex Gins Protein Psf2
Molecule annotation
1
DNA Replication Complex Gins Protein Psf3
Molecule annotation
1
DNA Replication Complex Gins Protein Sld5
Molecule annotation
1
Cell Division Control Protein 45 Homolog
Molecule annotation
Nucleotide(1 molecule)
1
DNA (5'-d(p*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*t)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
5
ZINC IONZINC ION
2
2
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
3
3
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTERPHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
4
3
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303