6W3H: Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys

PDB ID: 6W3HDownload
MMDB ID: 188785
PDB Deposition Date: 2020/3/9
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 3.38  Å
Source Organism:
Similar Structures:
Biological Unit for 6W3H: dimeric; determined by author
Molecular Components in 6W3H
Label Count Molecule
Proteins (2 molecules)
1
ATV FC
Molecule annotation
1
Transferrin Receptor Protein 1,transferrin Receptor Protein 1
(Gene symbol: TFRC)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
2
alpha-D-mannopyranosealpha-D-mannopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303