6VQL: CRYSTAL STRUCTURE OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 (IRAK4-WT) COMPLEX WITH A NICOTINAMIDE INHIBITOR

PDB ID: 6VQLDownload
MMDB ID: 189271
PDB Deposition Date: 2020/2/5
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.069  Å
Source Organism:
Similar Structures:
Biological Unit for 6VQL: tetrameric; determined by author and by software (PISA)
Molecular Components in 6VQL
Label Count Molecule
Proteins (4 molecules)
4
Interleukin-1 Receptor-associated Kinase 4
(Gene symbol: IRAK4)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
4
6-[(1,3-benzothiazol-6-yl)amino]-4-(cyclopropylamino)-N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]pyridine-3-carboxamide6-[(1,3-benzothiazol-6-yl)amino]-4-(cyclopropylamino)-N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]pyridine-3-carboxamide
2
10
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303