6V6F: Crystal structure of Q61L KRAS(GMPPNP)-NF1(GRD)-SPRED1(EVH1) complex

PDB ID: 6V6FDownload
MMDB ID: 190118
PDB Deposition Date: 2019/12/5
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.542  Å
Source Organism:
Similar Structures:
Biological Unit for 6V6F: trimeric; determined by author and by software (PISA)
Molecular Components in 6V6F
Label Count Molecule
Proteins (3 molecules)
1
Sprouty-related, Evh1 Domain-containing Protein 1
(Gene symbol: SPRED1)
Molecule annotation
1
Neurofibromin
(Gene symbol: NF1)
Molecule annotation
1
Gtpase Kras
(Gene symbol: KRAS)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
4
FORMIC ACIDFORMIC ACID
2
1
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
3
1
MAGNESIUM IONMAGNESIUM ION
4
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303