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6TO7:
Crystal structure of the Orexin-1 receptor in complex with suvorexant at 2.29 A resolution
PDB ID:
6TO7
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MMDB ID:
182792
PDB Deposition Date:
2019/12/11
Updated in MMDB:
2020/03
Experimental Method:
x-ray diffraction
Resolution:
2.26 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6TO7: monomeric; determined by author
Molecular Components in 6TO7
Label
Count
Molecule
Protein (1 molecule)
A
1
Orexin Receptor Type 1
(Gene symbol:
HCRTR1
)
Chemicals and Non-standard biopolymers (31 molecules)
1
1
[(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone
2
1
TETRAETHYLENE GLYCOL
3
1
CITRIC ACID
4
25
octyl 1-thio-beta-D-glucopyranoside
5
2
(1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate
6
1
SODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303