6TCA: Phosphorylated p38 and MAPKAPK2 complex with inhibitor

PDB ID: 6TCADownload
MMDB ID: 190379
PDB Deposition Date: 2019/11/5
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 3.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6TCA: dimeric; determined by author and by software (PISA)
Molecular Components in 6TCA
Label Count Molecule
Proteins (2 molecules)
1
MAP Kinase-activated Protein Kinase 2
(Gene symbol: MAPKAPK2)
Molecule annotation
1
Mitogen-activated Protein Kinase 14
(Gene symbol: MAPK14)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamideN-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303