6RQC: Cryo-EM structure of an MCM loading intermediate

PDB ID: 6RQCDownload
MMDB ID: 190994
PDB Deposition Date: 2019/5/15
Updated in MMDB: 2020/08
Experimental Method:
electron microscopy
Resolution: 4.4  Å
Source Organism:
Similar Structures:
Biological Unit for 6RQC: 14-meric; determined by author
Molecular Components in 6RQC
Label Count Molecule
Proteins (12 molecules)
1
Origin Recognition Complex Subunit 1
(Gene symbol: ORC1)
Molecule annotation
1
Origin Recognition Complex Subunit 2
(Gene symbol: ORC2)
Molecule annotation
1
Origin Recognition Complex Subunit 3
(Gene symbol: ORC3)
Molecule annotation
1
Origin Recognition Complex Subunit 4
(Gene symbol: ORC4)
Molecule annotation
1
Origin Recognition Complex Subunit 5
(Gene symbol: ORC5)
Molecule annotation
1
Origin Recognition Complex Subunit 6
(Gene symbol: ORC6)
Molecule annotation
1
DNA Replication Licensing Factor Mcm2
(Gene symbol: MCM2)
Molecule annotation
1
DNA Replication Licensing Factor Mcm3
(Gene symbol: MCM3)
Molecule annotation
1
DNA Replication Licensing Factor Mcm4
(Gene symbol: MCM4)
Molecule annotation
1
Minichromosome Maintenance Protein 5
(Gene symbol: MCM5)
Molecule annotation
1
DNA Replication Licensing Factor Mcm6
(Gene symbol: MCM6)
Molecule annotation
1
DNA Replication Licensing Factor Mcm7
(Gene symbol: MCM7)
Molecule annotation
Nucleotides(2 molecules)
1
DNA (88-mer)
Molecule annotation
1
DNA (88-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
3
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
2
3
MAGNESIUM IONMAGNESIUM ION
3
4
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
4
5
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303