6RCW: Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-053

PDB ID: 6RCWDownload
MMDB ID: 177812
PDB Deposition Date: 2019/4/11
Updated in MMDB: 2019/09
Experimental Method:
x-ray diffraction
Resolution: 2.08  Å
Source Organism:
Similar Structures:
Biological Unit for 6RCW: monomeric; determined by author
Molecular Components in 6RCW
Label Count Molecule
Protein (1 molecule)
1
Camp-specific 3',5'-cyclic Phosphodiesterase 4D
(Gene symbol: PDE4D)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
1
ZINC IONZINC ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
14
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
1
2,3-DIHYDROXY-1,4-DITHIOBUTANE2,3-DIHYDROXY-1,4-DITHIOBUTANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303