6R4D: Aurora-A in complex with shape-diverse fragment 58

PDB ID: 6R4DDownload
MMDB ID: 175227
PDB Deposition Date: 2019/3/22
Updated in MMDB: 2019/07
Experimental Method:
x-ray diffraction
Resolution: 2.009  Å
Source Organism:
Similar Structures:
Biological Unit for 6R4D: monomeric; determined by author and by software (PISA)
Molecular Components in 6R4D
Label Count Molecule
Protein (1 molecule)
1
Aurora Kinase a
(Gene symbol: AURKA)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
CHLORIDE IONCHLORIDE ION
4
1
(1~{S},10~{S})-12-cyclobutyl-5-methyl-1-oxidanyl-10-propan-2-yl-9,12-diazatricyclo[8.2.1.0^{2,7}]trideca-2(7),3,5-trien-11-one(1~{S},10~{S})-12-cyclobutyl-5-methyl-1-oxidanyl-10-propan-2-yl-9,12-diazatricyclo[8.2.1.0^{2,7}]trideca-2(7),3,5-trien-11-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303