6Q13: CRYSTAL STRUCTURE OF LDHA IN COMPLEX WITH COMPOUND NCGC00420737-09 AT 2.00 A RESOLUTION

PDB ID: 6Q13Download
MMDB ID: 193081
PDB Deposition Date: 2019/8/2
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 6Q13: tetrameric; determined by author and by software (PISA)
Molecular Components in 6Q13
Label Count Molecule
Proteins (4 molecules)
4
L-lactate Dehydrogenase a Chain
(Gene symbol: LDHA)
Molecule annotation
Chemicals and Non-standard biopolymers (26 molecules)
1
4
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
2
6
2-[5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-3-{3-[(5-methylthiophen-2-yl)ethynyl]phenyl}-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid2-[5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-3-{3-[(5-methylthiophen-2-yl)ethynyl]phenyl}-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid
3
16
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303