6PBC: Structural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated mutations

PDB ID: 6PBCDownload
MMDB ID: 182916
PDB Deposition Date: 2019/6/13
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.46  Å
Source Organism:
Similar Structures:
Biological Unit for 6PBC: monomeric; determined by author and by software (PISA)
Molecular Components in 6PBC
Label Count Molecule
Protein (1 molecule)
1
1-phosphatidylinositol 4,5-bisphosphate Phosphodiesterase Gamma,1-phosphatidylinositol 4,5-bisphosphate Phosphodiesterase Gamma-1
(Gene symbol: Plcg1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
CALCIUM IONCALCIUM ION
2
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303