6OVA: Crystal Structure of TYK2 with novel pyrrolidinone inhibitor

PDB ID: 6OVADownload
MMDB ID: 184090
PDB Deposition Date: 2019/5/7
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6OVA: monomeric; determined by author and by software (PISA)
Molecular Components in 6OVA
Label Count Molecule
Protein (1 molecule)
1
Non-receptor Tyrosine-protein Kinase Tyk2
(Gene symbol: TYK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-({4-[(3S)-3-cyano-3-cyclopropyl-2-oxopyrrolidin-1-yl]pyridin-2-yl}amino)-N,N-dimethylpyridine-3-carboxamide6-({4-[(3S)-3-cyano-3-cyclopropyl-2-oxopyrrolidin-1-yl]pyridin-2-yl}amino)-N,N-dimethylpyridine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303