6J8H: Structure of human voltage-gated sodium channel Nav1.7 in complex with auxiliary beta subunits, huwentoxin-IV and saxitoxin (Y1755 down)

PDB ID: 6J8HDownload
MMDB ID: 172716
PDB Deposition Date: 2019/1/19
Updated in MMDB: 2019/11
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6J8H: trimeric; determined by author
Molecular Components in 6J8H
Label Count Molecule
Proteins (3 molecules)
1
Sodium Channel Subunit Beta-2
(Gene symbol: SCN2B)
Molecule annotation
1
Sodium Channel Protein Type 9 Subunit Alpha
(Gene symbol: SCN9A)
Molecule annotation
1
Sodium Channel Subunit Beta-1
(Gene symbol: SCN1B)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
11
2-acetamido-2-deoxy-beta-D-glucopyranose (Link to PubChem not yet available)2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
[(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate (Link to PubChem not yet available)[(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303