6I0B: Human butyrylcholinesterase in complex with the S enantiomer of a chlorotacrine-tryptophan multi-target inhibitor

PDB ID: 6I0BDownload
MMDB ID: 173659
PDB Deposition Date: 2018/10/25
Updated in MMDB: 2019/08
Experimental Method:
x-ray diffraction
Resolution: 2.384  Å
Source Organism:
Similar Structures:
Biological Unit for 6I0B: monomeric; determined by author and by software (PISA)
Molecular Components in 6I0B
Label Count Molecule
Protein (1 molecule)
1
Cholinesterase
(Gene symbol: BCHE)
Molecule annotation
Chemicals and Non-standard biopolymers (21 molecules)
1
8
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
alpha-L-fucopyranosealpha-L-fucopyranose
3
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
4
1
(2~{S})-2-azanyl-~{N}-[6-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(1~{H}-indol-3-yl)propanamide(2~{S})-2-azanyl-~{N}-[6-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(1~{H}-indol-3-yl)propanamide
5
3
GLYCEROLGLYCEROL
6
4
SULFATE IONSULFATE ION
7
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303