6GCX: Focal Adhesion Kinase catalytic domain in complex with irreversible inhibitor

PDB ID: 6GCXDownload
MMDB ID: 174864
PDB Deposition Date: 2018/4/19
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 1.553  Å
Source Organism:
Similar Structures:
Biological Unit for 6GCX: monomeric; determined by author and by software (PISA)
Molecular Components in 6GCX
Label Count Molecule
Protein (1 molecule)
1
Focal Adhesion Kinase 1
(Gene symbol: PTK2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2-[[2-[[4-[[[3,4-bis(oxidanylidene)-2-[2-(propanoylamino)ethylamino]cyclobuten-1-yl]amino]methyl]phenyl]amino]-5-chloranyl-pyrimidin-4-yl]amino]-~{N}-methyl-benzamide2-[[2-[[4-[[[3,4-bis(oxidanylidene)-2-[2-(propanoylamino)ethylamino]cyclobuten-1-yl]amino]methyl]phenyl]amino]-5-chloranyl-pyrimidin-4-yl]amino]-~{N}-methyl-benzamide
2
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303