6GCW: Focal Adhesion Kinase catalytic domain in complex with irreversible inhibitor

PDB ID: 6GCWDownload
MMDB ID: 174863
PDB Deposition Date: 2018/4/19
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 6GCW: dimeric; determined by author and by software (PISA)
Molecular Components in 6GCW
Label Count Molecule
Proteins (2 molecules)
2
Focal Adhesion Kinase 1
(Gene symbol: PTK2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
2-[[5-chloranyl-2-[[4-[[[1-[2-(propanoylamino)ethyl]-1,2,3-triazol-4-yl]methylamino]methyl]phenyl]amino]pyrimidin-4-yl]amino]-~{N}-methyl-benzamide2-[[5-chloranyl-2-[[4-[[[1-[2-(propanoylamino)ethyl]-1,2,3-triazol-4-yl]methylamino]methyl]phenyl]amino]pyrimidin-4-yl]amino]-~{N}-methyl-benzamide
2
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303