6FO0: CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial compound GSK932121

PDB ID: 6FO0Download
MMDB ID: 159829
PDB Deposition Date: 2018/2/5
Updated in MMDB: 2019/12
Experimental Method:
electron microscopy
Resolution: 4.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6FO0: eicosameric; determined by author and by software (PISA)
Molecular Components in 6FO0
Label Count Molecule
Proteins (20 molecules)
2
Cytochrome B-c1 Complex Subunit 1, Mitochondrial
(Gene symbol: UQCRC1)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit 2, Mitochondrial
(Gene symbol: UQCRC2)
Molecule annotation
2
Cytochrome B
(Gene symbol: CYTB)
Molecule annotation
2
Cytochrome C1, Heme Protein, Mitochondrial
(Gene symbol: CYC1)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit Rieske, Mitochondrial
(Gene symbol: UQCRFS1)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit 7
(Gene symbol: UQCRB)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit 8
(Gene symbol: UQCRQ)
Molecule annotation
2
Cytochrome B-c1 Complex Subunit 6, Mitochondrial
(Gene symbol: UQCRH)
Molecule annotation
2
Chain I/V
Molecule annotation
2
Cytochrome B-c1 Complex Subunit 9
(Gene symbol: UQCR10)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
2
3-chloro-6-(hydroxymethyl)-2-methyl-5-{4-[3-(trifluoromethoxy)phenoxy]phenyl}pyridin-4-ol3-chloro-6-(hydroxymethyl)-2-methyl-5-{4-[3-(trifluoromethoxy)phenoxy]phenyl}pyridin-4-ol
3
2
HEME CHEME C
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303