6F8X: Crystal structure of the PDE4D catalytic domain in complex with GEBR-26g

PDB ID: 6F8XDownload
MMDB ID: 162179
PDB Deposition Date: 2017/12/13
Updated in MMDB: 2018/05
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 6F8X: dimeric; determined by author and by software (PISA)
Molecular Components in 6F8X
Label Count Molecule
Proteins (2 molecules)
2
Camp-specific 3',5'-cyclic Phosphodiesterase 4D
(Gene symbol: PDE4D)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
2
ZINC IONZINC ION
2
4
MAGNESIUM IONMAGNESIUM ION
3
2
2-[(5~{R})-3-(3-cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-1,2-oxazol-5-yl]-~{N},~{N}-bis(2-hydroxyethyl)ethanamide2-[(5~{R})-3-(3-cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-1,2-oxazol-5-yl]-~{N},~{N}-bis(2-hydroxyethyl)ethanamide
4
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303